EDITORIAL FOCUS:

János Peti-Peterdi and Robert H. Chow

A novel tool to visualize the cell secretory pathway. Focus on "A fluorimetry-based ssYFP secretion assay to monitor vasopressin-induced exocytosis in LLC-PK₁ cells expressing aquaporin-2"
Am J Physiol Cell Physiol 295: C1473-C1473, 2008. First published October 29, 2008; doi:10.1152/ajpcell.00550.2008 [Full Text] [PDF]  

H. Moo Kwon

Protein misfolding in hypertonic stress: new insights into an old idea. Focus on "Genome-wide RNAi screen and in vivo protein aggregation reporters identify degradation of damaged protein as an essential hypertonic stress response"
Am J Physiol Cell Physiol 295: C1474-C1475, 2008. First published October 29, 2008; doi:10.1152/ajpcell.00548.2008 [Full Text] [PDF]  

TRANSLATIONAL PHYSIOLOGY:

Jaladanki N. Rao, Stephen V. Liu, Tongtong Zou, Lan Liu, Lan Xiao, Xian Zhang, Emily Bellavance, Jason X.-J. Yuan, and Jian-Ying Wang

Rac1 promotes intestinal epithelial restitution by increasing Ca²⁺ influx through interaction with phospholipase C-1 after wounding
Am J Physiol Cell Physiol 295: C1499-C1509, 2008. First published October 15, 2008; doi:10.1152/ajpcell.00232.2008 [Abstract] [Full Text] [PDF]  

MEMBRANE TRANSPORTERS, ION CHANNELS, AND PUMPS:

Kate E. O'Driscoll, William J. Hatton, Heather R Burkin, Normand Leblanc, and Fiona C. Britton

Expression, localization, and functional properties of Bestrophin 3 channel isolated from mouse heart
Am J Physiol Cell Physiol 295: C1610-C1624, 2008. First published October 22, 2008; doi:10.1152/ajpcell.00461.2008 [Abstract] [Full Text] [PDF]  

Tin-Han Shih, Jiun-Lin Horng, Pung-Pung Hwang, and Li-Yih Lin

Ammonia excretion by the skin of zebrafish (Danio rerio) larvae
Am J Physiol Cell Physiol 295: C1625-C1632, 2008. First published September 24, 2008; doi:10.1152/ajpcell.00255.2008 [Abstract] [Full Text] [PDF]  

Patricia Hafner, Rosa Grimaldi, Paola Capuano, Giovambattista Capasso, and Carsten A. Wagner

Pendrin in the mouse kidney is primarily regulated by Cl^– excretion but also by systemic metabolic acidosis
Am J Physiol Cell Physiol 295: C1658-C1667, 2008. First published October 29, 2008; doi:10.1152/ajpcell.00419.2008 [Abstract] [Full Text] [PDF] [Supplemental Figures]  

MUSCLE CELL BIOLOGY AND CELL MOTILITY:

Luana Toniolo, Pasqua Cancellara, Lisa Maccatrozzo, Marco Patruno, Francesco Mascarello, and Carlo Reggiani

Masticatory myosin unveiled: first determination of contractile parameters of muscle fibers from carnivore jaw muscles
Am J Physiol Cell Physiol 295: C1535-C1542, 2008. First published October 8, 2008; doi:10.1152/ajpcell.00093.2008 [Abstract] [Full Text] [PDF]  

Kazuaki Nagayama and Takeo Matsumoto

Contribution of actin filaments and microtubules to quasi-in situ tensile properties and internal force balance of cultured smooth muscle cells on a substrate
Am J Physiol Cell Physiol 295: C1569-C1578, 2008. First published October 15, 2008; doi:10.1152/ajpcell.00098.2008 [Abstract] [Full Text] [PDF]  

RECEPTORS AND SIGNAL TRANSDUCTION:

Han Na Suh, Huang Thi Huong, Chang Hun Song, Jang Hern Lee, and Ho Jae Han

Linoleic acid stimulates gluconeogenesis via Ca²⁺/PLC, cPLA₂, and PPAR pathways through GPR40 in primary cultured chicken hepatocytes
Am J Physiol Cell Physiol 295: C1518-C1527, 2008. First published October 8, 2008; doi:10.1152/ajpcell.00368.2008 [Abstract] [Full Text] [PDF]  

Andrea Carranza, Patricia L. Musolino, Marcelo Villar, and Susana Nowicki

Signaling cascade of insulin-induced stimulation of L-dopa uptake in renal proximal tubule cells
Am J Physiol Cell Physiol 295: C1602-C1609, 2008. First published October 8, 2008; doi:10.1152/ajpcell.00090.2008 [Abstract] [Full Text] [PDF]  

Gary E. Striker, Francoiçe Praddaude, Oscar Alcazar, Scott W. Cousins, and Maria E. Marin-Castaño

Regulation of angiotensin II receptors and extracellular matrix turnover in human retinal pigment epithelium: role of angiotensin II
Am J Physiol Cell Physiol 295: C1633-C1646, 2008. First published October 15, 2008; doi:10.1152/ajpcell.00092.2008 [Abstract] [Full Text] [PDF]  

VASCULAR BIOLOGY:

Hideyuki Yamawaki, Kazuaki Saito, Muneyoshi Okada, and Yukio Hara

Methylglyoxal mediates vascular inflammation via JNK and p38 in human endothelial cells
Am J Physiol Cell Physiol 295: C1510-C1517, 2008. First published October 8, 2008; doi:10.1152/ajpcell.00252.2008 [Abstract] [Full Text] [PDF]  

Carl P. Nelson, Jonathon M. Willets, Noel W. Davies, R. A. John Challiss, and Nicholas B. Standen

Visualizing the temporal effects of vasoconstrictors on PKC translocation and Ca²⁺ signaling in single resistance arterial smooth muscle cells
Am J Physiol Cell Physiol 295: C1590-C1601, 2008. First published October 1, 2008; doi:10.1152/ajpcell.00365.2008 [Abstract] [Full Text] [PDF]  

Qiong Huang and Nader Sheibani

High glucose promotes retinal endothelial cell migration through activation of Src, PI3K/Akt1/eNOS, and ERKs
Am J Physiol Cell Physiol 295: C1647-C1657, 2008. First published October 22, 2008; doi:10.1152/ajpcell.00322.2008 [Abstract] [Full Text] [PDF]  

GROWTH, DIFFERENTIATION, AND APOPTOSIS:

Tina Rødgaard, Kenneth Schou, Martin B. Friis, and Else K. Hoffmann

Does the intracellular ionic concentration or the cell water content (cell volume) determine the activity of TonEBP in NIH3T3 cells?
Am J Physiol Cell Physiol 295: C1528-C1534, 2008. First published October 8, 2008; doi:10.1152/ajpcell.00081.2008 [Abstract] [Full Text] [PDF]  

Lauren W. Collison, Eric J. Murphy, and Christopher A. Jolly

Glycerol-3-phosphate acyltransferase-1 regulates murine T-lymphocyte proliferation and cytokine production
Am J Physiol Cell Physiol 295: C1543-C1549, 2008. First published October 29, 2008; doi:10.1152/ajpcell.00371.2007 [Abstract] [Full Text] [PDF]  

PROTEIN AND VESICLE TRAFFICKING, CYTOSKELETON:

Keith P. Choe and Kevin Strange

Genome-wide RNAi screen and in vivo protein aggregation reporters identify degradation of damaged proteins as an essential hypertonic stress response
Am J Physiol Cell Physiol 295: C1488-C1498, 2008. First published October 1, 2008; doi:10.1152/ajpcell.00450.2008 [Abstract] [Full Text] [PDF]  

EXTRACELLULAR MATRIX, CELL INTERACTIONS:

Wei-Chun Wei, Hsi-Hui Lin, Meng-Ru Shen, and Ming-Jer Tang

Mechanosensing machinery for cells under low substratum rigidity
Am J Physiol Cell Physiol 295: C1579-C1589, 2008. First published October 15, 2008; doi:10.1152/ajpcell.00223.2008 [Abstract] [Full Text] [PDF]  

CELLULAR AND MITOCHONDRIAL METABOLISM:

Jorge Suarez, Yong Hu, Ayako Makino, Eduardo Fricovsky, Hong Wang, and Wolfgang H. Dillmann

Alterations in mitochondrial function and cytosolic calcium induced by hyperglycemia are restored by mitochondrial transcription factor A in cardiomyocytes
Am J Physiol Cell Physiol 295: C1561-C1568, 2008. First published October 22, 2008; doi:10.1152/ajpcell.00076.2008 [Abstract] [Full Text] [PDF]  

NERVOUS SYSTEM CELL BIOLOGY:

Guangze Li and James E. Olson

Purinergic activation of anion conductance and osmolyte efflux in cultured rat hippocampal neurons
Am J Physiol Cell Physiol 295: C1550-C1560, 2008. First published October 15, 2008; doi:10.1152/ajpcell.90605.2007 [Abstract] [Full Text] [PDF]  

METHODS IN CELL PHYSIOLOGY:

Paula Nunes, Udo Hasler, Mary McKee, Hua A. J. Lu, Richard Bouley, and Dennis Brown

A fluorimetry-based ssYFP secretion assay to monitor vasopressin-induced exocytosis in LLC-PK₁ cells expressing aquaporin-2
Am J Physiol Cell Physiol 295: C1476-C1487, 2008. First published September 17, 2008; doi:10.1152/ajpcell.00344.2008 [Abstract] [Full Text] [PDF] [Supplemental Videos]  

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